HP2 LABORATOIRE

Our goal is to investigate the influence of hypoxia, sleep and exercise on cardiometabolic health trajectories with molecular, pathophysiological and epidemiological approaches. HP2 LABORATOIRE is a research Inserm unit based out of Grenoble Alpes Univeristy and Grenoble Alpes University hospital, France. The future of medicine relies on the ability to assess disease risk at an individual level, understand molecular mechanisms underlying progression of disease and aggregation of comorbidities and early initiation of personalized interventions. To achieve this goal of precision and personalized medicine in obstructive sleep apnea (OSA) and advice for value-based care, we propose to conduct the following program: Use real world data, well-managed cohorts and wearable monitoring for enabling physiological profiling and identification of homogeneous groups of interest. Identify main obstructive sleep apnea clusters (composed of relevant individual, social and environmental context fact...